Destroy completely; damage irreparably.
You have ruined my life.
You have ruined my car by pouring sugar in the tank!+ More
An irrecoverable state of devastation and destruction.
You have brought ruin on this entire family.
Burn, Burn Down, Fire - destroy by fire.
Desolate, Devastate, Lay Waste To, Ravage, Scourge, Waste - cause extensive destruction or ruin utterly.
Do A Job On - destroy completely or make ugly or useless.
Sleepy, Sleepy-Eyed, Sleepyheaded - ready to fall asleep; "I feel sleepy".
Curse, Curse Word, Cuss, Expletive, Oath, Swearing, Swearword - profane or obscene expression usually of surprise or anger; "Curse on you".
How - To what extent, amount, or degree; "How do I look ?".
Apologise, Apologize - acknowledge faults or shortcomings or failing; "I apologize for what I did".